So the LORD God said to the serpent, “Because you have done this,
Cursed are you above all the livestock
and all the wild animals!
You will crawl on your belly
and you will eat dust
all the days of your life.
And I will put enmity
between you and the woman,
and between your offspring and hers;
he will crush your head,
and you will strike his heel.”
Genesis 3 : 14,15 (New International Version)
God passes sentence; and he begins where the sin began, with the serpent. The devil’s instruments must share in the devil’s punishments. Under the cover of the serpent, the devil is sentenced to be degraded and accursed of God; detested and abhorred of all mankind:
also to be destroyed and ruined at last by the great Redeemer, signified by the breaking of his head. War is proclaimed between the Seed of the woman and the seed of the serpent. It is the fruit of this enmity, that there is a continual warfare between grace and corruption, in the hearts of God’s people. Satan, by their corruptions, buffets them, sifts them, and seeks to devour them.
Taken From Matthew Henry’s Concise Commentary.